Frequently Asked Questions

At-home ketamine therapy is a physician-supervised treatment where patients take prescribed sublingual (under-the-tongue) ketamine tablets or troches in the comfort of their own home. Kalm Health provides telehealth consultations with licensed providers who evaluate patients and prescribe ketamine for treatment-resistant depression, anxiety, PTSD, and chronic pain. Medications are compounded by licensed pharmacies and shipped directly to your door.

Kalm Health's standard plan starts at $124 per month, which includes your telehealth consultation, prescription, and compounded medication shipped to your home. For patients requiring higher doses (above 1200mg per month), we offer a higher-dose plan at $175 per month billed as $349 every two months. Dosing is determined by the treating provider based on an individual medical evaluation.

Ketamine is approved by the FDA as an anesthetic. The FDA has not approved it for depression, anxiety, PTSD or other psychiatric conditions, so prescribing it for those is off label. Ketamine is a Schedule III controlled substance, licensed healthcare providers can legally prescribe it off-label for conditions like depression, anxiety, PTSD, and chronic pain. Kalm Health operates in full compliance with federal and state telehealth regulations.

A licensed provider may evaluate whether ketamine treatment is appropriate for adults with conditions such as treatment-resistant depression, major depressive disorder, generalized anxiety disorder, PTSD and OCD. Whether it is appropriate for you is determined by the provider. It works differently from traditional antidepressants by targeting the glutamate system and promoting neuroplasticity.

Kalm Health offers a telehealth clinical care program with licensed providers, pricing starting at $124/month, no clinic visits needed, and ongoing provider support. Kalm does not publish comparisons to other providers — Kalm provides affordable at-home sublingual ketamine with ongoing support.

Common side effects include temporary dissociation, dizziness, nausea, drowsiness, and changes in perception. These typically last 1-2 hours and resolve on their own. Less common but more serious risks include effects on the bladder and urinary tract, cognitive effects with heavy chronic use, and misuse or dependence. See our Medical Disclaimers page. Patients should not drive or operate heavy machinery for at least 6 hours after dosing.

Responses vary from person to person, and some people do not respond at all. Ketamine acts through a different mechanism than traditional antidepressants. Kalm does not guarantee any particular result or timeline. Results vary, and Kalm providers work with you to optimize your protocol over time.

In most cases, no. Ketamine can often be used alongside existing antidepressants and other psychiatric medications. Your Kalm Health provider will review all current medications during your consultation and advise on any adjustments. Never stop prescribed medications without consulting your provider.

1. Visit kalmhealth.org and select your plan
2. Complete a brief medical intake questionnaire
3. Schedule a telehealth consultation with a licensed provider
4. If approved, your medication ships directly from a licensed pharmacy
5. Begin treatment with ongoing provider support

The entire process typically takes 3-7 business days.

Most insurance plans do not currently cover off-label ketamine therapy, though HSA and FSA accounts can often be used. At $124/month, Kalm Health makes ketamine therapy accessible without insurance — significantly less than IV clinics at $400-800 per session.

Kalm is currently available in 44 states and the District of Columbia. Kalm is not currently able to initiate services for patients located in Alabama, Arkansas, Delaware, Louisiana, Minnesota, or Rhode Island. Availability depends on state telehealth regulations and controlled substance prescribing laws, and can change. Visit kalmhealth.org or contact our team to check availability in your state.

Care is delivered by licensed clinicians who hold a license in the state where you are located at the time of your visit. Kalm Health's Medical Director is Dr. Adetunji Williams, MD. Your prescribing clinician reviews your intake, decides whether treatment is appropriate for you, and remains responsible for your treatment plan.

If a clinician prescribes treatment, your prescription is sent to Strive Pharmacy, a licensed pharmacy. Kalm Health does not manufacture, dispense, or ship medication. A prescription is issued only when a licensed clinician determines that treatment is clinically appropriate for you.

Sublingual ketamine dissolves under the tongue and can be taken at home. IV ketamine requires clinic visits with an IV line. While IV has higher bioavailability (~100% vs 25-35%), sublingual ketamine is effective at appropriate doses, costs a fraction of IV treatments, and allows consistent dosing in a comfortable home environment.

Ketamine can temporarily raise blood pressure. Uncontrolled hypertension may be a contraindication, but patients with well-managed blood pressure may still be candidates. Your provider will evaluate your cardiovascular health during consultation.

Treatment duration varies. Some patients use it for a few months to break through a depressive episode, while others benefit from longer-term maintenance. There's no mandatory minimum commitment — your provider will regularly reassess and adjust your plan.

Ketamine has potential for misuse and dependence, and that risk is higher at doses above those prescribed or outside a medical setting. Ketamine is Schedule III — lower dependence potential than opioids or amphetamines. Kalm providers monitor closely, use appropriate dosing, and screen for risk factors. Therapeutic doses are much lower than recreational use.

Yes. Kalm Health is a licensed telehealth provider that connects patients with licensed healthcare providers who hold active DEA registrations. All prescriptions are filled by licensed U.S. compounding pharmacies, and Kalm operates in full compliance with federal and state telehealth regulations. Prescription treatment is not guaranteed and is determined by the treating provider.

Yes. If you are currently receiving ketamine treatment elsewhere, tell your provider. Your Kalm provider will review your treatment history, current dosage, and goals during your consultation to ensure a smooth transition. If you were on a higher dose with your previous provider, Kalm can accommodate that — your Kalm provider will determine your dose based on their own clinical assessment. You can start the process at kalmhealth.org with a free prequalification assessment.

Dosing is determined by the treating licensed provider based on an individual medical evaluation, your history and your response. Kalm does not promise or guarantee any particular dose. For patients who need higher doses (above 1200mg per month), Kalm offers a higher-dose plan at $175/month (billed as $349 every two months). Your provider will work with you to find the right therapeutic dose based on your individual response and clinical needs.